Immunologic enhancement of b16 melanoma growth
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چکیده
منابع مشابه
Fibronectin enhancement of directed migration of B16 melanoma cells.
The migration of B16 melanoma cells into porous nitrocellulose filters fitted between the upper and lower compartments of blindwell chemotactic chambers was examined by light microscopy. Human plasma fibronectin placed in the lower compartment of such chambers enhanced in a time-, temperature-, and dose-dependent manner the directed migration of B16 cells into the filter. Fibronectin placed eit...
متن کاملEffect of anti-B16 melanoma monoclonal antibody on established murine B16 melanoma liver metastases.
The administration of anti-B16 monoclonal antibody of the IgG2b isotype to mice bearing established B16 melanoma liver metastases caused a significant and consistent reduction of up to 90% in the number of these metastases. No reduction in the number of metastases was noted when antigenically unrelated tumor or nonspecific immunoglobulin were employed. The antibody-mediated antitumor effect was...
متن کاملSodium ascorbate enhancement of carbidopa-levodopa methyl ester antitumor activity against pigmented B16 melanoma.
We report here the single and combined antitumor activity on B16 melanoma in female C57BL/6 X DBA/2F1 mice bearing s.c. tumors of sodium ascorbate, carbidopa-levodopa methyl ester, and dietary phenylalanine and tyrosine deficiency. Groups of 15 mice were fed continuously one of three test diets both with and without sodium ascorbate (30 mg/ml) in the drinking water beginning 2 weeks before inoc...
متن کاملHyperthermic enhancement of rhodamine 123 cytotoxicity in B16 mouse melanoma cells in vitro.
The effect of elevated temperature on cytotoxicity of rhodamine 123 (R123) was tested in vitro on B16 mouse melanoma cells. Simultaneous 1-h exposure to R123 and hyperthermia (43 degrees C for 1 h) resulted in marked enhancement of R123 cytotoxicity. Thermal enhancement of R123 cytotoxicity occurred at temperatures as low as 38 degrees C. Heat treatment (43 degrees C for 1 h) given immediately ...
متن کاملAn amelanotic variant of B16 malignant melanoma.
MATERIALS AND METHODS Murine malignant melanoma (B16) cells tolerant to 10 and 30 pg of BrdU per ml were maintained for more than one year in culture medium lacking the analog. The analog-containing environment was also eliminated by the injection of cells at several subcultures into host animals. Cells withdrawn from BrdU retained the enlarged, flattened, nonpigmented morphology that is charac...
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ژورنال
عنوان ژورنال: Cancer
سال: 1988
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19880501)61:9<1792::aid-cncr2820610912>3.0.co;2-0